BACKGROUND Public health programs are tasked with educating the community on pertinent public health topics, but it is unclear how effective these programs are and if they are acceptable for learners. Currently, these programs are delivered via a variety of platforms including in-person, virtually, and over the telephone. Sickle cell trait (SCT) education for parents of children with this trait is one of many education programs provided by the Ohio Department of Health. The novel SCTaware videoconference education program was developed by a research team after central Ohio’s standard program transitioned from in-person to telephone-only during the COVID-19 pandemic. OBJECTIVE Our objective was to investigate acceptability of format and engagement with the SCTaware education, and to assess parental worry about having a child with SCT before and after receiving SCTaware. METHODS This was a single center, prospective study of English-speaking parents of children RESULTS Fifty-five participants completed follow-up surveys after receiving standard SCT telephone education and then completing SCTaware. Most (n=51) participants reported that the SCTaware content and visuals were very easy to understand (n=47) and facilitated conversation with the Educator (n=42). All said the visuals were respectful and trustworthy, helped them understand content better, and that their questions were addressed. Nearly two-thirds (62%) reported that the pictures appeared very personal and applied to them. The Educator noted most participants (n=45) were engaged and asked questions (n=45), despite having to manage distractions during their education sessions. Many participants (n=33) reported some level of worry following telephone-only education; this was significantly reduced after receiving SCTaware (p < 0.0001). CONCLUSIONS Our results suggest that SCTaware is acceptable and engaging to parents. While telephone education may make SCT education more accessible, these findings suggest that many parents experience significant worry about their child with SCT after these sessions. A study to evaluate SCTaware’s effectiveness at closing parents’ SCT knowledge gaps is ongoing.