Stressor-evoked fMRI activity, cardiovascular reactivity, and subclinical atherosclerosis in midlife adults
- Resource Type
- Authors
- Rasero, Javier; Verstynen, Timothy; DuPont, Caitlin; Kraynak, Thomas; Barinas-Mitchell, Emma; Scudder, Mark; Kamarck, Thomas; Sentis, Amy; Leckie, Regina; Gianaros, Peter
- Source
- Subject
- Health Psychology
Neuroscience and Neurobiology
Biological Psychology
fMRI
Cognitive Psychology
health neuroscience
Life Sciences
Social and Behavioral Sciences
MSIT
behavioral disciplines and activities
blood pressure reactivity
cardiovascular disease risk
FOS: Psychology
Stroop task
Psychology
psychological phenomena and processes
- Language
This study tests whether among a midlife and otherwise healthy sample of approximately 600 adults who participated in 2 studies with comparable assessment protocols, the magnitude of stressor-evoked systolic blood pressure reactivity averaged across two psychological challenges (Stroop color-word and multi-source interference [MSIT] tasks) reliably mediate the predictive association between task-averaged and concurrent stressor-evoked fMRI activity and carotid artery intima-media thickness, a measure of pre-clinical atherosclerosis.