Modulation of the chaperone-like activity of bovine alpha-crystallin.
- Resource Type
- Article
- Authors
- Clark, John I.; Huang, Qing-Ling
- Source
- Proceedings of the National Academy of Sciences of the United States of America. 12/24/96, Vol. 93 Issue 26, p15185. 5p. 2 Diagrams, 2 Charts, 5 Graphs.
- Subject
- *GLUTATHIONE
*PANTETHINE
*HEAT shock proteins
*BIOCHEMICAL mechanism of action
*PHYSIOLOGY
- Language
- ISSN
- 0027-8424
Evaluates the effects of pantethine (P), glutathione (G) and selected chemical reagents on the anti-aggregation activity of bovine heat shock protein, alpha-crystallin. Action of alpha-crystallin on the aggregation of betaL-crystallin or alcohol dehydrogenase (ADH); Effect of P and G on chaperone-like activity of alpha-crystallin on aggregation of betaL-crystallins and ADH.