Cage-pond integration system is a new model for enhancing productivity of pond aquaculture system. A field trial was conducted using African catfish ( Clarias gariepinus) and Nile tilapia ( Oreochromis niloticus) in cages and carps in earthen ponds. There were four treatments replicated five times: (1) carps in ponds without cage, (2) tilapia at 30 fish m−3 in cage and carps in open pond, (3) catfish at 100 fish m−3 in cage and carps in open pond, (4) tilapia and catfish at 30 and 100 fish m−3, respectively, in separate cages and carps in open pond. The carps were stocked at 1 fish m−2. The cage occupied about 3% of the pond area. The caged tilapia and catfish were fed and the control ponds were fertilized. Results showed that the combined extrapolated net yield was significantly higher ( P < 0.05) in the catfish, tilapia and carps integration system (9.4 ± 1.6 t ha−1 year−1) than in the carp polyculture (3.3 ± 0.7 t ha−1 year−1). The net return from the tilapia and carps (6860 US$ ha−1 year−1) and catfish, tilapia and carps integration systems (6668 US$ ha−1 year−1) was significantly higher than in the carp polyculture (1709 US$ ha−1 year−1) ( P < 0.05). This experiment demonstrated that the cage-pond integration of African catfish and Nile tilapia with carps is the best technology to increase production; whereas integration of tilapia and carp for profitability. [ABSTRACT FROM AUTHOR]