The ordered array of nanovoids innanoporous networks, such ashoneycomb, Kagome, and square, provides a molecular template for theaccommodation of “guest molecules”. Compared with thecommonly studied guest molecules featuring high symmetry evenly incorporatedinto the template, guest molecules featuring lower symmetry are rareto report. Herein, we report the formation of a distinct patternedsuperlattice of guest molecules by selective trapping of guest moleculesinto the honeycomb network of trimesic acid (TMA). Two distinct surfacepatterns have been achieved by the guest inclusion induced adaptivereconstruction of a 2D molecular nanoporous network. The honeycombnetworks can synergetically tune the arrangement upon inclusion ofthe guest molecules with different core size but similar peripheralsgroups, resulting in a trihexagonal Kagome or triangular patterns. [ABSTRACT FROM AUTHOR]