Pioneer axon guidance by unc-129, a C. elegans TGF-...
- Resource Type
- Article
- Authors
- Colavita, Antonio; Krishna, Srikant; Zheng, Hong; Padgett, Richard W.; Culotti, Joseph G.
- Source
- Science; 7/31/1998, Vol. 281 Issue 5377, p706-709, 4p, 9 Color Photographs, 4 Diagrams, 3 Graphs
- Subject
- Axons
Genetics
Transforming growth factors
- Language
- ISSN
- 00368075
Reports that UNC-129 mediates expression of dorsoventral polarity information required for axon guidance and guided cell migrations in Caenorhabditis elegans. UNC-129 as encoding a member of the transforming growth factor-beta (TGF-...) superfamily of secreted signaling molecules and is expressed in dorsal rows of body wall muscles.