Microglial activation of p38 contributes to scorpion envenomation-induced hyperalgesia.
- Resource Type
- Article
- Authors
- Niu, Qing-Shan; Jiang, Feng; Hua, Li-Ming; Fu, Jin; Jiao, Yun-Lu; Ji, Yong-Hua; Ding, Gang
- Source
- Biochemical & Biophysical Research Communications. Oct2013, Vol. 440 Issue 3, p374-380. 7p.
- Subject
- *MICROGLIA
*PROTO-oncogenes
*SCORPION venom
*HYPERALGESIA
*MESOBUTHUS martensii
*NEUROTOXIC agents
- Language
- ISSN
- 0006-291X
Highlights: [•] Spinal microglia was activated in novel pain model, BmK I animal model. [•] The activation of microglia is p38 dependent. [•] The inhibitor of p38 suppressed microglial activation and pain-related behaviors. [ABSTRACT FROM AUTHOR]