An Elevated Estimated Pulmonary Arterial Systolic Pressure, Whenever Measured, Is Associated with Excess Mortality in Adults with Sickle Cell Disease.
- Resource Type
- Article
- Authors
- Lorch, Daniel; Spevack, Daniel; Little, Jane
- Source
- Acta Haematologica. 2011, Vol. 125 Issue 4, p225-229. 5p. 1 Chart, 1 Graph.
- Subject
- *TRICUSPID valve
*MORTALITY
*SICKLE cell anemia
*PULMONARY artery
*KIDNEY diseases
*PATIENTS
- Language
- ISSN
- 0001-5792
The article asserts that an elevated tricuspid regurgitant (TR) jet velocity is associated with long-term risk of excess mortality among patients suffering from sickle cell disease (SCD). The authors examined the impact of elevated TR jet on more than 200 patients with SCD and found that a mildly elevated estimated pulmonary arterial systolic pressure was a predictor of mortality among SCD patients. They also revealed that depressed renal function also has a connection with mortality risk.