Abstract: Study Objective: To compare the success of orotracheal intubation in 62 seconds or less using the GlideScope video laryngoscope (GVL) and a 60° or 90° angled stylet with reverse loading of the endotracheal tube (ETT). Design: Prospective, randomized study. Setting: Operating room of a university hospital. Patients: 120 ASA physical status I, II, and III adult patients undergoing elective surgery requiring general anesthesia with orotracheal intubation. Interventions: Patients were randomly allocated to two groups (n = 60 each); both groups received general anesthesia and neuromuscular relaxation. A conventional ETT was styleted and then bent from its straight configuration just above the cuff, either at 60° or 90° against its concave natural curve (reverse loading). Four attending anesthesiologists, who were blinded as to stylet assignment (the 60° or 90° group), intubated the tracheas of all patients with the GVL using either the primary or secondary stylet. Measurements: The primary outcome was success of orotracheal intubation in 62 seconds or less. The secondary outcome was actual time to intubation (TTI). Main Results: The odds ratio (OR) for intubation success was higher in the 90° group than the 60° group (OR = 10.41; P < 0.03), as evidenced by 59 of 60 patients whose tracheas were intubated successfully within 62 seconds, compared with 51 of 60 patients in the 60° group. Seven of the 9 failures were due to inability of the 60° stylet to reach the glottic opening. The three remaining failures were associated with TTI of more than 62 seconds. Conclusions: The 90° angled malleable stylet with reverse loading of the ETT provided more reliable ETT delivery to the glottic opening and had a higher success rate than the 60° stylet. [Copyright &y& Elsevier]