Probiotic properties of folate producing Streptococcus thermophilus strains
- Resource Type
- Article
- Authors
- Iyer, Ramya; Tomar, S.K.; Kapila, Suman; Mani, Jiju; Singh, Rameshwar
- Source
- Food Research International. Jan2010, Vol. 43 Issue 1, p103-110. 8p.
- Subject
- *PROBIOTICS
*STREPTOCOCCUS thermophilus
*DAIRY products
*BILE salts
*ENZYME activation
*FOLIC acid
- Language
- ISSN
- 0963-9969
Abstract: This study aimed at assessing the probiotic potential of two high folate producing Streptococcus thermophilus strains (RD102 and RD104) isolated from Indian fermented milk products by both in vitro and in vivo tests. These strains were able to survive at pH 2.5 and 2% bile with a good bile salt hydrolase activity, cell surface hydrophobicity and sensitivity to most of the clinically important antibiotics. On evaluation for gastrointestinal transit tolerance these showed a viable count of 5logcfumL−1 and 7logcfumL−1, respectively in simulated gastrointestinal juice of pH 2.0 and 2% bile. During the in vivo feeding trial in mice the strains showed a viable count of about 7logcfug−1 faeces and 6logcfug−1 of large intestine, respectively. These strains were hence observed to possess favorable strain specific probiotic properties and have the potential to be a source of novel probiotics. [Copyright &y& Elsevier]