A Novel Genetic Pathway for Sudden Cardiac Death via Defects in the Transition Between...
- Resource Type
- Article
- Authors
- Nguyen-Tran, Van T.B.; Kubalak, Steven W.
- Source
- Cell. 09/01/2000, Vol. 102 Issue 5, p672. 12p. 3 Color Photographs, 1 Diagram, 3 Graphs.
- Subject
- *CARDIAC arrest
*CELL lines
*GENETICS
- Language
- ISSN
- 0092-8674
Provides evidences for a novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages. Generation of HF-1b, a cardiac transcription factor related to the SP-1 gene family; Preferential expression of HF-1b; Effect of widespread conduction defects and ventricular arrythmogenesis in HF-1b.