Correction of high-rate motion for photoacoustic microscopy by orthogonal cross-correlation.
- Resource Type
- Article
- Authors
- Zou, Zilong; Mao, Qiuqin; Cheng, Renxiang; Tao, Chao; Liu, Xiaojun
- Source
- Scientific Reports. 2/21/2024, Vol. 14 Issue 1, p1-10. 10p.
- Subject
- *ACOUSTIC imaging
*MICROSCOPY
*PHOTOACOUSTIC spectroscopy
*BRAIN imaging
*PHOTOACOUSTIC effect
- Language
- ISSN
- 2045-2322
Photoacoustic imaging is a promising technology for in vivo imaging. However, its imaging performance can be hampered by motion artifacts, especially when dealing with high-rate motion. In this paper, we propose an orthogonal motion correction method that utilizes cross-correlation along orthogonal scan directions to extract accurate motion displacements from the photoacoustic data. The extracted displacements are then applied to remove artifacts and compensate for motion-induced distortions. Phantom experiments demonstrate that the proposed method can extract the motion information and the structural similarity index measurement after correction is increased by 26.5% and 11.2% compared to no correction and the previous correction method. Then the effectiveness of our method is evaluated in vivo imaging of a mouse brain. Our method shows a stable and effective performance under high-rate motion. The high accuracy of the motion correction method makes it valuable in improving the accuracy of photoacoustic imaging. [ABSTRACT FROM AUTHOR]