This article discusses the first successful living donor uterus transplant performed in the UK. The procedure was done on a 34-year-old woman with Mayer-Rokitansky-Küster-Hauser syndrome, and her 40-year-old sister served as the donor. The recipient underwent follow-up appointments to monitor her progress, and the surgical procedure involved unique aspects compared to previous cases. The article also highlights the risks and considerations associated with uterine transplantation, such as infection and the need for immunosuppression. The authors stress the importance of expertise, regulation, and accurate monitoring in establishing clinical uterine transplantation programs. [Extracted from the article]