Objectives: Coronary artery bypass grafting (CABG) is crucial in the management of ischemic heart disease,this work aimed to relate the early post- operative effects of off-pump versus on-pump coronary artery bypass in patients with early stage renal dysfunction. Methods: Our Primary outcome variables were; requirement of inotropic support, duration of ICU stay, stroke, renal failure,myocardial infarction and death within 30 days after operation. There were two groups of patients; Group-I (On-pump group) and Group-II (Off-pump Group). SPSS V17 was used for data analysis. Results: There was statistically significant difference between the two studied groups as regard mean operative time it was 224.6± 57.54 in on-pump and 175.25± 43.07 in off-pump group The number of grafts conducted in off-pump group was significantly fewer. There was no statistically significant difference between the two studied groups as regard post-operative follow up data including mechanical ventilation, hospital stay, myocardial infarction, stroke, surgical reopening and hospital mortality. Statistically significant difference between the two studied groups as regard other post-operative complications including dobutamine use, arrhythmia, blood transfused, creatinine level and dialysis. Conclusions: Off pump technique appears to be a better procedure in patients with preoperative renal dysfunction. [ABSTRACT FROM AUTHOR]