Photoinduced reductive Reformatsky reaction of α-haloesters and aldehydes or ketones by cooperative dual-metal catalysis.
- Resource Type
- Article
- Authors
- Chen, Qi-Long; Mao, Le; Pan, Yi-Fan; Cai, Heng; Zhang, Xiao-Ming; Zhang, Fu-Min; Ma, Ai-Jun; Peng, Jin-Bao; Tu, Yong-Qiang
- Source
- Chemical Communications. 12/18/2023, Vol. 59 Issue 97, p14427-14430. 4p.
- Subject
- *REFORMATSKY reaction
*CATALYSIS
*KETONES
*ALDEHYDES
*AMINATION
*METALS
- Language
- ISSN
- 1359-7345
A photoinduced reductive Reformatsky reaction by cooperative dual-metal catalysis is described. This methodology enables the implementation of this venerable reaction in environmentally friendly conditions, obviating the need for a stoichiometric amount of metals. A broad range of synthetically useful β-hydroxy esters can be efficiently prepared in moderate to high yields using this protocol. [ABSTRACT FROM AUTHOR]