Reference 1 Wang R, Wang M, Wang S. An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes. After treatment of matrine, oxymatrine, cytisine and sophocarpine, the images of calcium fluorescence and bright field were acquired intuitively and the fluorescence intensity was analysed quantitatively using IncuCyte™ S3 ZOOM cell imaging system. After treatment with matrine, oxymatrine, cytisine and sophocarpine, A the images of ROS fluorescence and bright field were acquired intuitively using IncuCyte™ S3 ZOOM cell imaging system and B, C the fluorescence intensity was analysed quantitatively using TissueQuest 6.0. [Extracted from the article]