trans -3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide.
- Resource Type
- Article
- Authors
- Liu, Dayi; Guillot, Régis; Robin, Sylvie; Aitken, David J.
- Source
- Molbank. Sep2023, Vol. 2023 Issue 3, pM1726. 6p.
- Subject
- *AZETIDINE
*HYDROGEN bonding
*X-ray diffraction
- Language
- ISSN
- 1422-8599
trans-3-Benzyloxycarbonylamino-1-methyl-3-(methylcarbamoyl)azetidine-1-oxide was prepared by stereoselective oxidation of the corresponding azetidine precursor. The stable molecule was characterized in a low-polarity solution by IR, 1H-NMR and 13C-NMR, and in the solid state as a co-crystal with water by X-Ray diffraction. The N-oxide function made a strong intramolecular 7-membered ring hydrogen bond with the methyl amide NH in solution and formed an intermolecular H-bond with the carbamate NH in a neighboring molecule in the solid state. [ABSTRACT FROM AUTHOR]