Part I shows that (A) PS1V97L + ligation, PS1V97L + sham, and wild type (WT) + ligation mice were subjected to laser speckle blood flow monitoring to determine their cerebral blood flow (CBF) at 1 week, 5 weeks, and 5 months after surgery. Part I shows that (A) PS1V97L + ligation, PS1V97L + sham, and wild type (WT) + ligation mice were subjected to laser speckle blood flow monitoring to determine their cerebral blood flow (CBF) at 1 week, 5 weeks, and 5 months after surgery. [Extracted from the article]