The design of a hybrid Hematology I course (prepandemic) was adopted for Hematology II and facilitated our conversion of Hematology II into a fully remote course by fall 2020, after the university went into remote instruction. When the university suspended face-to-face (F2F) classes in March 2020, only the laboratory final exam was pending for Hematology I, and it was therefore administered remotely. Because students had taken another F2F practical exam before lockdown, we were able to compare the two. There was a significant difference between the practical examination grades for the online versus F2F exams: 94% vs. 77% mean scores, respectively. However, there was no difference between the written portion of the exams. In this article, we report the final lab and lecture grades for both courses. In spring 2021, our students completed their clinical practicums with our hospital affiliates and received scores of > 90%. We also report the performance of students who sat for the American Society of Clinical Pathology Board of Certification (BOC) examination for medical laboratory scientists. All students who appeared in the BOC examination performed satisfactorily in the hematology subdiscipline. These external assessments are positive objective benchmarks for our courses and students. [ABSTRACT FROM AUTHOR]