Association between Severe Acute Respiratory Syndrome Coronavirus 2 Infection (Coronavirus Disease 2019) and Lupus Anticoagulant-Hypoprothrombinemia Syndrome: A Case Report and Literature Assessment.
- Resource Type
- Article
- Authors
- Monti, Marta; Martini, Tiziano; Pengo, Vittorio; Poletti, Giovanni; Pedrazzi, Paola; Biasoli, Chiara; Giovacchini, Maddalena; Fasano, Tommaso
- Source
- Seminars in Thrombosis & Hemostasis. Jul2023, Vol. 49 Issue 5, p558-560. 3p.
- Subject
- *COVID-19
*CORONAVIRUS diseases
*ANTIPHOSPHOLIPID syndrome
*SARS-CoV-2
- Language
- ISSN
- 0094-6176
Diagnosis of LAC (lupus anticoagulant) was made on day 3 and was associated with high titer aPS/PT (anti phosphatidyl-serine/prothrombin) antibodies of IgG isotype. Among the tests that study the presence of circulating antiphospholipid antibodies, the so-called lupus anticoagulant (LA) is considered the main risk factor for venous and arterial thromboembolic disease. [6] Like most cases of LA and antiphospholipid antibodies reported to be associated with COVID-19, [7][8] the LA in our case was transient and not the characteristic of an antiphospholipid (antibody) syndrome. [Extracted from the article]