Development of a by-product-free strategy for the synthesis of oxazoline from N-acetylglucosamine.
- Resource Type
- Article
- Authors
- Zhou, Sen; Bo, Ma; Tang, Feng; Liu, Wenqiang; Li, Xin; Chen, Baoquan; Shang, Shiying; Huang, Wei; Li, Yaohao; Tan, Zhongping
- Source
- New Journal of Chemistry. 5/28/2023, Vol. 47 Issue 20, p9532-9535. 4p.
- Subject
- *OXAZOLINE synthesis
*N-acetylglucosamine
- Language
- ISSN
- 1144-0546
This study focused on the CDMBI-mediated synthesis of GlcNAc oxazoline. Through our research, we uncovered and characterized a previously unreported by-product. We proposed a mechanism for its formation and developed a new strategy to prevent its occurrence. These findings represent an important step towards gaining a deeper understanding of this reaction and may provide a new avenue for optimizing the oxazoline synthesis. [ABSTRACT FROM AUTHOR]