The patient then underwent mitral valve neoplasm removal and mitral valve replacement. The neoplasm was sent for culture and mNGS detection; mNGS detected I Bartonella henselae i and no other pathogens were detected, the neoplasm culture was negative. To the Editor: Infective endocarditis (IE) is a serious and life-threatening disease, with a yearly incidence of approximately three to 10 per 100,000.[1] Anti-infection is the cornerstone of the treatment of IE. [Extracted from the article]