Keywords: allergen; China; Der p 23; house dust mite; IgE sensitization EN allergen China Der p 23 house dust mite IgE sensitization 226 229 4 02/20/23 20230201 NES 230201 Abbreviations CRD component-resolved diagnosis HDM house dust mite Key messages Major HDM sensitizers were the Der p 1, Der f 2, Der p 2 in China. Between the Central and Northern regions, the specific IgE levels of Der p 1, Der p 2, Der f 2 and Der p 23 were higher in the Central region, while no significant difference was found in other allergens. Therefore, the major HDM allergens in China were Der p 1, Der f 2, Der p 2, while Der f 1, Der p 23, Der p 21, Der p 7, Der p 5 and Der p 10 are minor allergens. [Extracted from the article]