A novel resin (PS-TMMA) with double functional groups exhibited high adsorption selectivity toward 99TcO4− from the coexisting fission products (Sr, Eu, Dy, Cs) in 0.1–1 mol/L HCl. On the contrary, in neutral medium Kd of PS-TMMA resin towards lanthanide elements was much higher than Tc. The results of column chromatography showed that light lanthanide was firstly penetrated on the column. Using 0.01 mol/L 2-hydroxyisobutyric acid as eluent, the adsorbed lanthanides could be effectively eluted at pH 3.03, and the light and heavy lanthanides were partially separated in effluents. [ABSTRACT FROM AUTHOR]