In this paper, phosphomolybdic acid (HPMo) solution was chosen as a synthetic medium and active ingredient to replace hydrochloric acid, and the thick porous wall silicon composite based on HPMo (HPMo@OMS) was prepared by the one-step co-condensation method, which simplified the preparation process and improved the stability of the molecular sieve framework structure. The composite materials have the same ordered 2D hexagonal mesoporous structure as SBA-15. Compared to the traditional SBA-15 loaded HPMo (HPMo@SBA-15) synthesized in hydrochloric acid solution, the characterization results showed that the pore wall thickness of HPMo@OMS is about 2 nm thicker than the HPMo@SBA-15. Under mild experimental conditions, the catalyst has high desulfurization activity, and the removal rate of sulfur-containing substrate reaches 100%. In addition, after 10 desulfurization cycles, the Mo content of the composites recovered by centrifugation 13.74HPMo@OMS was only 1.67% by ICP-AES, the results after ten cycles of experiments showed that the removal rate of DBT could still reach 93.5%. [Display omitted] • One-step co-condensation method with easy preparation to improve atomic economy. • Taking phosphomolybdic acid as acidic medium is consistent with green chemistry idea. • The increase in pore wall thickness enhances the catalytic stability of the catalyst. • Highly efficient catalytic oxidation desulfurization performance. [ABSTRACT FROM AUTHOR]