B Introduction: b Augmented renal clearance (ARC) leads to supraphysiologic drug clearance and reduced exposure to renally eliminated medications such as vancomycin. Adult patients admitted to an ICU for trauma on vancomycin within 10 days of injury were screened. B Methods: b This prospective, single center, PK study included 6 critically ill trauma patients with ARC (defined as a creatinine clearance [CrCl] >120 mL/min) admitted to a level-1 trauma, academic medical center. [Extracted from the article]