Aims. The purpose of the present study was to explore the relationship between marital adjustment, coping strategies, social support and psychological distress among infertile women. Method. The data was taken from 150 infertile women from both government and private hospitals. Purposive sampling technique was used to recruit the sample. Psychological distress scale (Kessler, 2002) was used to measure the psychological distress in women with infertility. Moreover, marital adjustment scale was used to assess the level of marital adjustment. Result. Result revealed Significant Negative association between Marital Adjustment, Coping Strategies, Social Support and psychological distress. Furthermore, results showed significant prediction between Marital Adjustment, Coping Strategies, Social Support and Psychological Distress. Conclusion. Moreover, Results revealed higher level of coping strategies reduce the level of psychological distress and improved marital adjustment. [ABSTRACT FROM AUTHOR]