Hold the fold: how delayed folding aids protein secretion.
- Resource Type
- Article
- Authors
- McCaul, Nicholas; Braakman, Ineke
- Source
- EMBO Journal. 12/1/2022, Vol. 41 Issue 23, p1-3. 3p.
- Subject
- *PROTEIN folding
*CARRIER proteins
*SIGNAL peptides
*PROTEIN transport
*SECRETION
- Language
- ISSN
- 0261-4189
In bacteria, N‐terminal signal peptides mark proteins for transport across the plasma membrane. A recent study by Smets et al (2022) followed the folding of a pair of structural twins to shed light on how evolution has optimised the secretory process. [ABSTRACT FROM AUTHOR]