Dynamic combinatorial libraries of a dimercapto-pillar[5]arene.
- Resource Type
- Article
- Authors
- Luo, Jinwen; Guo, Yunlong; Li, Ping; Sue, Andrew C.-H.; Cheng, Chuyang
- Source
- Chemical Communications. 8/11/2022, Vol. 58 Issue 62, p8646-8649. 4p.
- Subject
- *LIBRARIES
*MOIETIES (Chemistry)
*COLUMNS
- Language
- ISSN
- 1359-7345
We report the synthesis and dynamic covalent chemistry (DCvC) of an A1/A2-dimercapto-functionalized pillar[5]arene (Di-SH-P5). The introduction of thiol moieties into this macrocyclic host makes it an effective building block for making a dynamic combinatorial library (DCL), giving rise to a set of cyclic trimers with intriguing host–guest properties as the dominant constituents. [ABSTRACT FROM AUTHOR]