Until 1991, observation was the standard of care for macular holes (MHs). 42 Ling L, Liu Y, Zhou B. Inverted internal limiting membrane flap technique versus internal limiting membrane peeling for vitrectomy in highly myopic eyes with macular hole-induced retinal detachment: an updated meta-analysis. BMC Ophthalmol. 2020; 20:, 11. 41 Yu JG, Wang J, Xiang Y. Inverted internal limiting membrane flap technique versus internal limiting membrane peeling for large macular holes: a meta-analysis of randomized controlled trials. In this technique, instead of the standard complete ILM separation from the MH, the ILM is peeled toward the center of the MH without complete separation from the edges of the MH. [Extracted from the article]