Outcome in PCNSL patients and its association with PD-L1+ leukocytes in the tumor microenvironment.
- Resource Type
- Article
- Authors
- Abdulla, Maysaa; Hollander, Peter; Lindskog, Cecilia; Sundström, Christer; Enblad, Gunilla; Saft, Leonie; Amini, Rose-Marie
- Source
- Acta Oncologica. Jul2022, Vol. 61 Issue 7, p824-829. 6p. 1 Chart, 1 Graph.
- Subject
- *BIOPSY
*CONFIDENCE intervals
*LEUCOCYTES
*IMMUNOHISTOCHEMISTRY
*LOG-rank test
*B cell lymphoma
*FISHER exact test
*MANN Whitney U Test
*CANCER patients
*CHEMORADIOTHERAPY
*GENE expression profiling
*IMMUNOPHENOTYPING
*KAPLAN-Meier estimator
*CHI-squared test
*DESCRIPTIVE statistics
*DATA analysis software
*PROPORTIONAL hazards models
*SYMPTOMS
CENTRAL nervous system tumors
- Language
- ISSN
- 0284-186X
The article informs about Outcome in Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (PCNSL) patients and its association with PD-L1þ leukocytes in the tumor microenvironment. Topics include using immune checkpoint inhibitors and immunological tolerance modifiers in treating various malignancies; and hematological malignancies have been disappointing, except for classical Hodgkin lymphoma (cHL).