Cascade Reaction of 3-Phenacylideneoxindoles with Trimethylsilyl Cyanide: Synthesis of Furan-Fused 1,3-Benzodiazepin-2-one Derivatives.
- Resource Type
- Article
- Authors
- Ma, Jing; Li, Shao-Yi; Aisikaer, Ailipire; Li, Xiao-Juan
- Source
- Synlett. 2022, Vol. 33 Issue 6, p559-562. 4p.
- Subject
- *CYANIDES
*FURAN derivatives
- Language
- ISSN
- 0936-5214
A cascade reaction of 3-phenacylideneoxindoles with trimethylsilyl cyanide is described. This method provides an efficient route for the synthesis of furan-fused 1,3-benzodiazepin-2-one derivatives by simply refluxing a reaction mixture of various 3-phenacylideneoxindoles with trimethylsilyl cyanide in the presence of H2 O and K2 CO3. [ABSTRACT FROM AUTHOR]