INVESTIGATION OF PLASMA CELL‐FREE DNA (CFDNA) AS A NOVEL BIOMARKER OF INFLAMMATION AND DISEASE SEVERITY IN EQUINE COLIC PATIENTS.
- Resource Type
- Article
- Authors
- Source
- Equine Veterinary Education; Sep2021 Supplement S1, Vol. 33, p22-23, 2p
- Subject
- Cell-free DNA
Colic
Circulating tumor DNA
Calcitonin
- Language
- ISSN
- 09577734
INVESTIGATION OF PLASMA CELL-FREE DNA (CFDNA) AS A NOVEL BIOMARKER OF INFLAMMATION AND DISEASE SEVERITY IN EQUINE COLIC PATIENTS Median extracted cfDNA concentrations were significantly higher in colic patients relative to healthy controls ( I p i < 0.0001) and in colic patients with SIRS (score >=2) compared to non-SIRS cases ( I p i = 0.010). We hypothesised that cfDNA in equine plasma would be measurable using a compact fluorometer, be elevated in colic patients vs. healthy horses, and be significantly different among clinically relevant groupings of colic patients. [Extracted from the article]