Detection of SARS‐CoV‐2‐specific memory B cells to delineate long‐term COVID‐19 immunity.
- Resource Type
- Article
- Authors
- Thieme, Constantin J.; Abou‐el‐Enein, Mohamed; Fritsche, Enrico; Anft, Moritz; Paniskaki, Krystallenia; Skrzypczyk, Sarah; Doevelaar, Adrian; Elsallab, Magdi; Brindle, Nicola; Blazquez‐Navarro, Arturo; Seibert, Felix S.; Meister, Toni L.; Pfaender, Stephanie; Steinmann, Eike; Witzke, Oliver; Westhoff, Timm H.; Stervbo, Ulrik; Heine, Guido; Roch, Toralf; Babel, Nina
- Source
- Allergy. Aug2021, Vol. 76 Issue 8, p2595-2599. 5p.
- Subject
- *B cells
*COVID-19
*MONONUCLEAR leukocytes
*B cell receptors
*PSYCHONEUROIMMUNOLOGY
*IMMUNITY
- Language
- ISSN
- 0105-4538
Specific labelling with SARS-CoV-2 S-protein and difference between COVID-19 patients and healthy individuals was restricted to B SB MEMORY sb -cells and not observed for other B cell subsets (Figure 2D-G). Keywords: COVID-19; long-term immunity; memory B cells; SARS-CoV-2 EN COVID-19 long-term immunity memory B cells SARS-CoV-2 2595 2599 5 07/19/21 20210801 NES 210801 The COVID-19 pandemic has led to devastating health outcomes with the death toll exceeding two million cases as of February 2021. Detection of SARS-CoV-2-specific memory B cells to delineate long-term COVID-19 immunity (B) Representative example for the detection of dual-labelled SARS-CoV-2 S-protein-binding B cells and quantification of antigen-specific B cell subsets. [Extracted from the article]