Robin Sequence (RS) is a rare condition leading to orofacial anomalies, including cleft palate. Evidence suggests children with RS have poor long-term speech and language outcomes, even in comparison to those with isolated cleft palate. This study compared speech and language outcomes of children with isolated cleft palate (ICP) to children with cleft palate and RS (CPRS). A retrospective case-note review was completed of 74 matched children (37 ICP; 37 CPRS). Speech and language assessment at 18-months, three and five years provided data for palatal function and articulation. At age five years, children with CPRS had significantly more frequent and severe articulation errors than children with ICP. Palatal function across the two groups was not significantly different. Expressive and receptive language at three years did not differ. Results support previous studies highlighting the severity and frequency of articulation errors associated with CPRS. Further longitudinal investigation into language outcomes is recommended. [ABSTRACT FROM AUTHOR]