The timing and location India–Asia collision is crucial to understanding the evolution of the Himalayan–Tibetan orogen and global climate change; however, estimates of the timing of the India–Asia collision and the size of Greater India remain highly controversial. We report here the first reliable early Eocene paleomagnetic results from the Zhepure Formation limestone in the Tethyan Himalaya (TH). Both positive fold and reversal tests indicate a primary origin. The tilt‐corrected site‐mean direction is Ds = 332.6°, Is = 20.1°, ks = 90.9, α95 = 2.8° (N = 30). The site‐mean inclination increased from 20.1° to 27.5° after inclination shallowing correction, yielding a paleopole at 61.2°N, 337.3°E, A95 = 2.6° and a corresponding paleolatitude of 15.2° ± 2.6°N for the reference point (29.5°N, 91.0°E). Our new paleomagnetic results, together with the reliable Cretaceous to Paleogene paleomagnetic results from the TH, Lhasa terrane and Indian craton, suggest that there was ∼900–1,140 km north‐south crustal shortening occurred between the TH and the Indian craton, and that India collided with Asia at no later than ∼51–49.5 Ma. Plain Language Summary: The India–Asia collision is among the most intriguing topics in earth sciences because of its influence on global climate and Cenozoic topography. However, several questions still remain unanswered, such as: how big was Greater India? When, where, and how did the India collide with Asia? We report the first reliable early Eocene paleopole from the TH and assess the timing of the India–Asia collision and the size of Greater India. Our results suggest a relatively small Greater India, and that India collided with Asia at no later than ∼51–49.5 Ma. The constraints on the India–Asia collision indicated by our data provide new boundary conditions for the history of the Himalayan–Tibetan orogen and global climate change. Key Points: The Tethyan Himalaya (TH) was located at 15.2° ± 2.6°N at ∼51–49.5 MaThere was ∼900–1,140 km north‐south crustal shortening occurred between the TH and the Indian cratonIndia collided with Asia at no later than ∼51–49.5 Ma [ABSTRACT FROM AUTHOR]