Palliative care is characterized by having an integral and multidisciplinary approach with multiple benefits for patients with advanced disease. Its development in Latin America continues to be heterogeneous, based on individual or group willingness. Nonetheless, it is slowly advancing with government led strategies. The present chapter reviews the published peer reviewed and gray literature on the development, current state and idiosyncrasy of palliative care in this region. Overall, there is a progressive increase in palliative care with efforts to increase the implementation of clinical programs, education, opioid availability and investigation. However, many countries still have scarce access to services, let alone education. Efforts must be made to expand the current availability in a collaborative and interdisciplinary manner since future needs will be overwhelming for our countries' healthcare capacities. [ABSTRACT FROM AUTHOR]