Revisit of metformin treatment in polycystic ovarian syndrome.
- Resource Type
- Article
- Authors
- Lam, P. M.; Cheung, L. P.; Haines, C.
- Source
- Gynecological Endocrinology. Jul2004, Vol. 19 Issue 1, p33-39. 7p.
- Subject
- *HYPOGLYCEMIC agents
*DIABETES complications
*INSULIN resistance
*HORMONES
*INSULIN
*DRUG resistance
- Language
- ISSN
- 0951-3590
Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women; its traditional pharmacological therapy mainly addresses short-term symptom control and does not correct the associated long-term metabolic risks. Recently, there has been increasing evidence that insulin resistance has an important implication in the pathogenesis of PCOS and that insulin-sensitizing drugs are a useful therapeutic approach. Therefore this review aims to discuss the current evidence on the use of metformin, a commonly used insulin-sensitizing agent, in treating both the short-term and the long-term problems of women with PCOS. [ABSTRACT FROM AUTHOR]