The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of nucleic acid (RNA and DNA) vaccines.
- Resource Type
- Article
- Authors
- Kim, Denny; Robertson, James S.; Excler, Jean-Louis; Condit, Richard C.; Fast, Patricia E.; Gurwith, Marc; Pavlakis, George; Monath, Thomas P.; Smith, Jonathan; Wood, David; Smith, Emily R.; Chen, Robert T.; Kochhar, Sonali
- Source
- Vaccine. Jul2020, Vol. 38 Issue 34, p5556-5561. 6p.
- Subject
- *RNA
*GENETIC vectors
*DNA
*VIRAL vaccines
*VACCINE safety
- Language
- ISSN
- 0264-410X
Nucleic acid (DNA and RNA) vaccines are among the most advanced vaccines for COVID-19 under development. The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) has prepared a standardized template to describe the key considerations for the benefit-risk assessment of nucleic acid vaccines. This will facilitate the assessment by key stakeholders of potential safety issues and understanding of overall benefit-risk. The structured assessment provided by the template can also help improve communication and public acceptance of licensed nucleic acid vaccines. [ABSTRACT FROM AUTHOR]