Objectives: The primary aim of this study was to develop an analytical tool based on conformance requirements (CRs) identified in ISO 15189:2012, which can be used by internal auditors to evaluate the extent of management review input information as specified in Subclause 4.15.2 (Review input) of ISO 15189:2012. Methods: The CRs were identified in Subclause 4.15.2 of ISO 15189:2012 and its referred subclauses for quantification purposes by content analysis. Results: A total of 25 CRs were identified in Subclause 4.15.2 of ISO 15189:2012 and these 25/399 (6.3%) CRs are distributed in the 'strategic management' stage of the ISO 15189:2012 process-based quality management system model. A further 252 CRs were identified in Subclause 4.15.2 of ISO 15189:2012 referred subclauses. These 26/477 (5.5%) CRs are distributed in the 'process control, design and planning' stage and 226/252 (90%) CRs are in the 'process evaluation and improvement' stage. The results were used for the development of management review input checklists and a conformity status map to support the interpretation. Conclusions: The application of a quantitative approach to facilitate internal auditing of the effectiveness of management review performance should improve the quality of information that feeds into the management review which, in turn, influences the crafting of organisational strategy.