Synthesis of 2-Imidazolines via Palladium-Catalyzed Cyclization Reaction of 2,3-Allenyl Amines and Aryl Iodides.
- Resource Type
- Article
- Authors
- Liu, Yue; Zhang, Cheng; Liang, Xiaoxia; Zeng, Xianzhong; Lu, Rongmei; Fang, Zixuan; Wang, Shaoyu; Liu, Yanjun; Hu, Jinxing
- Source
- Synthesis. 2020, Vol. 52 Issue 6, p901-908. 8p.
- Subject
- *AROMATIC amines
*ARYL iodides
*CARBON-carbon bonds
*IMIDAZOLINES
- Language
- ISSN
- 0039-7881
An effective method for the synthesis of polysubstituted 2-imidazoline derivatives via palladium-catalyzed cyclization of 2,3-allenyl amines with aryl iodides is described. This pure domino process allows the formation of new carbon–carbon and carbon–nitrogen bonds in a single synthetic operation. [ABSTRACT FROM AUTHOR]