To further demonstrate the role of miR-765 in chemosensitization, we used miR-765 agomiR, a cholesterol-conjugated 2'-O-methyl-modified miR-765 exhibiting The physiological relevance of the APE1/miR-765 interaction was further established by evaluating the endogenous expression patterns of miR-765 and APE1 in (A) APE1 and miR-765 expression are inversely correlated in osteosarcoma samples. Two groups according to miR-765 expression level, and APE1 expression showed considerable differences between the miR-765 low and miR-765 high groups (p=0.0034. [Extracted from the article]