Two new daphnane diterpenes from the roots of Stelleropsis tianschanica.
- Resource Type
- Article
- Authors
- Zhao, Dan; Shi, Lei-Ling; Guo, Xiong-Fei; Ma, Guo-Xu; Han, Jian-Wei; Yang, Jun-Shan; Xu, Jian-Guo; Zhang, Jing
- Source
- Journal of Asian Natural Products Research. Dec2018, Vol. 20 Issue 12, p1116-1122. 7p.
- Subject
- *CELL lines
*HYDROCARBON analysis
*APOPTOSIS
*HERBAL medicine
*HYDROCARBONS
*CHINESE medicine
*MOLECULAR structure
*PLANT roots
*STATISTICS
*PHYTOCHEMICALS
*DATA analysis
*PHYSIOLOGY
- Language
- ISSN
- 1028-6020
Two new daphnane diterpenes named tianchaterpenes A and B were isolated from the roots of Stelleropsis tianschanica. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Compounds 1 and 2 were evaluated for their cytotoxic activities against HeLa and HCT-8 cell lines. The results showed that all compounds displayed weak cytotoxicities to the HeLa cells and were inactive to the HCT-8 cells. [ABSTRACT FROM AUTHOR]