Abstract Effects of tropical cyclones (TCs) on dissolved oxygen (DO) in subsurface waters (20–200 m) over the Oxygen Minimum Zones (OMZs) in the Bay of Bengal (BoB) are examined based on Argo and satellite data. Five TCs (Hudhud, Five, Vardah, Maarutha and Mora) during 2013–2018 are considered. Analyses reveal three types of DO temporal variability caused by the storm-induced mixing and upwelling. The first type features temporal DO increases in subsurface waters (37–70 m) caused mainly by intense vertical mixing and downwelling. The second type features DO reductions in subsurface waters after the storms attributed to storm-induced upwelling. The third type features temporal DO increases at depths between 40 and 79 m and decreases at depths between 80 and 150 m due to the combined effect of strong vertical mixing and upwelling. These three types of DO responses can occur in different areas, depending on TC intensity, translational speed and Ekman pumping. The temporal DO variability is also influenced by the shallow oxycline (58.3 ± 16.7 m), mesoscale eddies and biochemical processes. Due to TC intensification, a pre-existing oceanic cyclonic eddy produced a large upwelling and induced a long time of DO decrease in the subsurface layer. This study suggests three different types of DO responses along the TC track in the OMZ, which is useful to evaluate the influence of TCs on the OMZ. Graphical abstract Unlabelled Image Highlights • Three different types of DO responses to tropical cyclones were observed in the central Bay of Bengal • Storm-induced temporal variability of DO was affected by the shallow oxycline, mesoscale eddies and biochemical processes • Tropical cyclones with slow translational speeds can result in DO reduction and OMZ intensification over the Bay of Bengal [ABSTRACT FROM AUTHOR]