Plasma Cell–Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients.
- Resource Type
- Article
- Authors
- Fung, Monica; Zompi, Simona; Seng, Hon; Hollemon, Desiree; Parham, Adama; Hong, David K; Bercovici, Sivan; Dolan, Estelle; Lien, Kathy; Teraoka, Justin; Logan, Aaron C; Chin-Hong, Peter
- Source
- Open Forum Infectious Diseases. Dec2018, Vol. 5 Issue 12, pN.PAG-N.PAG. 1p.
- Subject
- Language
- ISSN
- 2328-8957
Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell–free DNA next-generation sequencing test detected an uncommon presentation of Chlamydia trachomatis and recurrent and metastatic complications of Staphylococcus aureus bacteremia before standard microbiology. [ABSTRACT FROM AUTHOR]