Germline Genetic Testing for Pancreatic Ductal Adenocarcinoma at Time of Diagnosis.
- Resource Type
- Editorial
- Authors
- Syngal, Sapna; Furniss, C. Sloane
- Source
- JAMA: Journal of the American Medical Association. 6/19/2018, Vol. 319 Issue 23, p2383-2385. 3p.
- Subject
- *ADENOCARCINOMA
*PANCREATIC tumors
*GENETIC testing
*DUCTAL carcinoma
- Language
- ISSN
- 0098-7484
The authors offer observation on the study "Association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer" by C. Hu et al, wherein they report the findings of an investigation on the germline alterations in pancreatic ductal adenocarcinoma (PDAC). Topics discussed include overall prevalence of mutation of 21 candidate genes in unselected cases of PDAC, and implications of the study on the prevalence of germline mutations in pancreatic cancer.