Laser interstitial thermal therapy for the treatment of epilepsy: evidence to date.
- Resource Type
- Article
- Authors
- Shukla, Navika D.; Ho, Allen L.; Pendharkar, Arjun V.; Sussman, Eric S.; Halpern, Casey H.
- Source
- Neuropsychiatric Disease & Treatment. Sep2017, Vol. 13, p2469-2475. 7p.
- Subject
- *INTERSTITIAL lung diseases
*TREATMENT of epilepsy
*NEUROLOGIC manifestations of general diseases
*TEMPORAL lobe epilepsy
*PARTIAL epilepsy
- Language
- ISSN
- 1178-2021
Medically intractable epilepsy is associated with increased morbidity and mortality. For those with focal epilepsy and correlated electrophysiological or radiographic features, open surgical resection can achieve high rates of seizure control, but can be associated with neurologic deficits and cognitive effects. Recent innovations have allowed for more minimally invasive methods of surgical seizure control such as magnetic resonance-guided laser interstitial therapy (MRgLITT). MRgLITT achieves the goal of ablating seizure foci while preserving neuropsychological function and offering real-time feedback and monitoring of tissue ablation. This review summarizes the utilization of MRgLITT for mesial temporal lobe epilepsy and other seizure disorders. Overall, the efficacy of MRgLITT is comparable to that of open surgery and offers a less invasive approach in patients with significantly less morbidity. [ABSTRACT FROM AUTHOR]