Copper-mediated ortho C–H sulfonylation of benzoic acid derivatives with sodium sulfinates.
- Resource Type
- Article
- Authors
- Liu, Jidan; Yu, Lin; Zhuang, Shaobo; Gui, Qingwen; Chen, Xiang; Wang, Wenduo; Tan, Ze
- Source
- Chemical Communications. 4/14/2015, Vol. 51 Issue 29, p6418-6421. 4p.
- Subject
- *CARBON-hydrogen bonds
*BENZOIC acid
*REGIOSELECTIVITY (Chemistry)
*CHEMICAL research
*ORGANIC chemistry
- Language
- ISSN
- 1359-7345
Copper-mediated direct ortho C–H bond sulfonylation of benzoic acid derivatives with sodium sulfinates was achieved by employing an 8-aminoquinoline moiety as the bidentate directing group. Various aryl sulfones were synthesized in good yields with excellent regioselectivity. [ABSTRACT FROM AUTHOR]