One-pot aqueous synthesis of sub-10 nm responsive nanogels.
- Resource Type
- Article
- Authors
- Li, Luxian; Chang, Aiping; Hu, Yumei; Zhang, Laiying; Wu, Weitai
- Source
- Chemical Communications. 2013, Vol. 49 Issue 58, p6534-6536. 3p.
- Subject
- *NANOGELS
*ANALYTICAL chemistry
*AQUEOUS solutions
*COPOLYMERIZATION
*OLIGOMERIZATION
*CROSSLINKING (Polymerization)
*FLUOROURACIL
- Language
- ISSN
- 1359-7345
A strategy involving free radical copolymerization of a difunctional oligomer and a small-molecule crosslinker to give sub-10 nm nanogels is proposed. These nanogels can adapt to surrounding temperatures and regulate the release of a preloaded model anticancer drug 5-fluorouracil. [ABSTRACT FROM AUTHOR]