'Journal of Medicinal Chemistry ', vol: 59, pages: 1388-1409 (2016) Bavetsias, V, Lanigan, R M, Ruda, G F, Atrash, B, McLaughlin, M G, Tumber, A, Mok, N Y, Le Bihan, Y V, Dempster, S, Boxall, K J, Jeganathan, F, Hatch, S B, Savitsky, P, Velupillai, S, Krojer, T, England, K S, Sejberg, J, Thai, C, Donovan, A, Pal, A, Scozzafava, G, Bennett, J M, Kawamura, A, Johansson, C, Szykowska, A, Gileadi, C, Burgess-Brown, N A, Von Delft, F, Oppermann, U, Walters, Z, Shipley, J, Raynaud, F I, Westaway, S M, Prinjha, R K, Fedorov, O, Burke, R, Schofield, C J, Westwood, I M, Bountra, C, Müller, S, Van Montfort, R L M, Brennan, P E & Blagg, J 2016, ' 8-substituted pyrido[3,4-d ]pyrimidin-4(3 H )-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone lysine demethylase inhibitors ', Journal of Medicinal Chemistry, vol. 59, no. 4, pp. 1388-1409 . https://doi.org/10.1021/acs.jmedchem.5b01635 Journal of Medicinal Chemistry